ISongezo seSondlo sokuTya kwiBanga le-Oleanolic Acid Powder
Yintoni i-oleanolic acid?
I-Oleanolic acid (OA), i-hydroxyl pentacyclic triterpenoid acid (HPTA) yendalo efana ne-betulinic acid, i-ursolic acid;
Ungayifumana phi i-oleanolic acid?
Ezinye iziqhamo ezifana nama-apile, irharnati, ilamuni, iibhilberries, iminquma iqulethe i-oleanolic acid.
| Igama leHerb | Umxholo we-Oleanolic acid | Indlela yokuvavanya |
| Iprivet eqaqambileyo yatsho | 0.8028% | HPLC |
| Verbena Officinalis L | 0.071%-0.086% | HPLC |
| Prunella vulgaris L | 3.47%-4.46% | HPLC |
| Hemsley Chinansis Cogn. | 1.5%～2% | HPLC |
Okwangoku, isityalo saseTshayinaHemsley Chinansis Cogniseyeyona imathiriyeli yokurhweba yokukhupha i-oleanolic acid.
Hemsley Chinansis Cogn.Intshayelelo
Hemsleya chinensis Cogn.liyeza elihlala linyuka, ikwaliyeza lesiNtu lamaTshayina.
- Intsapho: Cucurbitaceae
- Isizwe: Gomphogyneae
- Uhlobo: Hemsleya
- Iintlobo: H. ethandekayo
I-herb isasazwa kumaphondo e-Guangxi, eSichuan, eGuizhou, eYunnan, eHubei, njl.
Izithako ezisebenzayo: iqulethe iHemslolide Mal, Ma3, H1; Chikusesusaponin-Iva; i-dihydro cucurbitacin F-25-acetate; dilydrocucurbitacin F; i-oleanolic acid-beta-Hlucosyloleanolate; Hemsamabilinin A; Cu-curbitacinⅡb-2-beta-D-glucopyranoside.
Ukukhutshwa kwe-Oleanolic acid kwi-Hemsleya Chinensis Cogn.
UPHICOTHO OLUYISISEKO
| Uhlahlelo | Inkcazo | Iziphumo | Iindlela zoVavanyo |
| Isivavanyi | ≥98.0% | 98.4% | HPLC |
| I-Organoleptic | |||
| Imbonakalo | Umgubo | Vumelana | I-Organoleptic |
| Umbala | I-off-white crystalline powder | Vumelana | I-Organoleptic |
| Ivumba | Ayinavumba kwaye ayinancasa | Vumelana | I-Organoleptic |
| Iimpawu zoMzimba | |||
| Ilahleko ekomisweni | ≤0.5% | 0.01% | USP |
| Intsalela | ≤0.1% | 0.039% | USP |
| Ukujikeleza okuthe ngqo | 75.0 ° -83.0 ° | 78.2° | CP2010 |
| Iintsimbi ezinzima | |||
| Iintsimbi ezinzima zizonke | 20ppm max | Vumelana | USPindlela II |
| Khokela (Pb) | 3ppm NMT | Vumelana | I-ICP-MS |
| IArsenic (As) | 2ppm NMT | Vumelana | I-ICP-MS |
| I-Cadmium (Cd) | 1ppm NMT | Vumelana | I-ICP-MS |
| IMercury (Hg) | 0.1ppm NMT | Vumelana | I-ICP-MS |
| Iimvavanyo zeMicrobiological | |||
| Ubalo lwepleyiti lulonke: | NMT 5,000 cfu/g | Vumelana | I-AOAC |
| Igwele kunye nokungunda: | NMT 300 cfu/g | Vumelana | I-AOAC |
| I-Salmonella: | Ibi | Vumelana | I-AOAC |
| E.Coli.: | Ibi | Vumelana | I-AOAC |
Umsebenzi
I-Oleanolic Acid (i-ursolic acid) yikhompawundi yendalo ye-triterpenoid efumaneka ngokubanzi kwizityalo, ezifana ne-bearberry, i-olive, i-blueberries, njl. Nazi iintshayelelo zobungcali kwi-Oleanolic Acid:
- Iziphumo zokulwa nokuvuvukala kunye ne-antioxidant:I-Ursolic acid inemisebenzi ebalulekileyo echasayo kunye ne-antioxidant. Inokunciphisa ukusabela okuvuthayo, ukuvimbela ukukhululwa kwabalamli abavuthayo, ukususa i-radicals yamahhala emzimbeni, kunye nokunciphisa umonakalo obangelwa uxinzelelo lwe-oxidative.
- Ukhuseleko lwesibindi:I-Ursolic acid inefuthe lokukhusela kwisibindi. Ikhuthaza ukuvuselelwa kweseli yesibindi kunye nokulungiswa, ukunciphisa umngcipheko wokulimala kwesibindi. I-Ursolic acid inokuthintela kwaye iphathe izifo zesibindi ezifana nesibindi esinamafutha ngokulawula i-fat metabolism esibindini.
- Umsebenzi wokulwa nethumba:Ursolic acid ineempembelelo inhibitory kwiiseli ithumba ezithile. Iyakwazi ukwenza umsebenzi wokulwa ne-tumor ngokulawula i-apoptosis yeeseli, inqanda ukwanda kunye nokuhlasela kweeseli ze-tumor, kunye nokulawula iindlela zokubonisa iiseli zomhlaza.
- Iziphumo ze-Hypoglycemic:I-Ursolic acid inefuthe elithile ekunciphiseni iswekile yegazi kunye nokuphucula umsebenzi we-pancreatic islet cell. Ikhuthaza ukukhuselwa kwe-insulin kunye nokuphucula ukuvakalelwa kwe-insulin, ngaloo ndlela inceda ukulawula isifo sikashukela kunye nokukhusela iingxaki ezinxulumene nazo.
- Umsebenzi we-antibacterial kunye ne-antiviral:Iasidi ye-Ursolic inomsebenzi othile we-antibacterial kunye ne-antiviral ngokuchasene neentlobo zebhaktheriya kunye neentsholongwane. Ithintela ukukhula kunye nokuphindaphinda kweebhaktheriya kunye neentsholongwane, ukunciphisa umngcipheko wosulelo kunye nesifo.
Ukongeza, i-ursolic acid ifunyenwe inokukhusela ulusu, iipropathi ze-antioxidant, kunye nokuchasana nesifo senhliziyo ye-ischemic.
