I-Casein phosphopeptides (CPP) luhlobo lwezongezo zokutya ezisebenzayo
I-Casein phosphopeptide yi-casein hydrolyzed yi-trypsin okanye i-trypsin, ehlanjululwayo kwaye ihlanjululwe. Ubume bayo obuphambili nguSer (P) - Ser (P) - Ser (P) - Glu Glu - (Ser: serine, Glu: glutamic acid, P: phosphate). Iintsalela ze-phosphoserine (- Ser (P) -) kwesi sakhiwo zikhona kumaqela kwaye zithwala iintlawulo ezimbi kwindawo ebuthakathaka ye-alkaline pH ye-intestinal, enokuthintela isenzo esongezelelweyo se-enzymes yokugaya kunye nokukhusela i-CPP kwi-hydrolysis eqhubekayo, okubangelwa ubukho obuzinzile. emathunjini. Uphando lwasekhaya lufumene ukuba i-molar ratio ye-nitrogen kwi-phosphorus kwi-CPP incinci, imfutshane i-peptide chain ye-CPP, kunye nokuphakama koxinano lwamaqela e-phosphate, okukhokelela ekucocekeni okuphezulu kwe-CPP kunye nokukhuthazwa okunamandla kokufunxa kwe-calcium kunye nokusetyenziswa.
I-calcium ifunxwa ngokulula kuphela xa ikhona kwimo ye-ion, kwaye kwiindawo ezingathathi hlangothi kunye ne-alkaline engenamandla, kulula ukwenza iityuwa ezinganyibilikiyo kunye ne-asidi ion kwaye ilahleke. Umphumo wokufunxa we-CPP kwi-calcium ubonakaliswa ikakhulu ngokukwazi ukubopha nge-calcium kwindawo engathathi hlangothi kunye ne-alkaline ebuthathaka, inqanda ukuveliswa kwe-insoluble precipitates, ukuphepha ukulahleka kwe-calcium, kwaye ekugqibeleni ifunxa ngokungahambi ngenxa yokwanda kwe-calcium concentration. Uphando lwangoku lubonisa ukuba impembelelo ye-CPP ekukhuthazeni ukufunxa kwe-calcium ibonakaliswa ikakhulu kule miba ilandelayo:
- (1) Ukukhuthaza ukufunxwa kwe-calcium emathunjini amancinci.
Ukutya okuziinkozo ekutyeni komntu kuqulethe inani elikhulu lezinto eziphezulu ze-phosphorus ezifana ne-phytic acid kunye ne-inositol hexaphosphate, edibanisa ne-calcium kwindawo ye-pH 7-8 ekupheleni kwamathumbu amancinci ukwenza i-calcium phosphate precipitates. I-CPP inokuthintela ukubunjwa kwe-calcium phosphate precipitation, igcine i-concentration ephezulu ye-calcium yamahhala, ikhuthaze ukuxutywa kwe-calcium, kwaye ibe enye indlela ye-vitamin D njengomgqugquzeli we-calcium absorption.
- (2) Ukukhuthaza ukusetyenziswa kwe-calcium ngamathambo.
Uvavanyo lwezilwanyana lubonisa ukuba i-CPP inokukhuthaza ukuxutywa kunye nokusetyenziswa kwe-calcium, yenza buthathaka umphumo we-osteoclast kwaye inqanda ukuchithwa kwamathambo.
- (3) Khuthaza ukusetyenziswa kwecalcium ngamazinyo.
Ngaphambili, bekukholelwa ukuba ukuhlafuna itshizi emva kokutya kunokuvuselela ukuphuma kwamathe, kuvumela amathe ealkaline ukuba athintele izinto ezineasidi kwiplaque yamazinyo kwi-enamel eyonakalisayo, enceda ukuthintela ukwenzeka kwamazinyo. Kwiminyaka yakutshanje, uphando lufumene ukuba i-CPP equlethwe kwitshizi inokubopha i-calcium ions ekutyeni kwi-caries yamazinyo, ukunciphisa i-enamel demineralization, kwaye ngaloo ndlela ifezekise iinjongo ze-anti caries.
Uphando luye lwafumanisa ukuba isidoda kwindawo yenkcubeko equlethe i-CPP inamandla aphezulu kakhulu okungena kwiiseli zeqanda kwaye inokunciphisa iqondo lokuhluka kwesidoda, okwenza uphuhliso lwe-embryonic luzinze ngakumbi. I-CPP inokuphucula i-bioavailability yee-ion zetsimbi ezifana nentsimbi, i-zinc, kunye ne-magnesium, kungoko yaziwa ngokuba yinto ye-peptide enomsebenzi wokuthwala isinyithi. Okwangoku, i-CPP isetyenziswe kwirayisi yekheri yabantwana, iziselo, itshungama kunye nokunye ukutya kunye neemveliso zempilo kumazwe angaphandle. Uphando kunye nokusetyenziswa kunyango lokunqongophala kwe-calcium kubantwana, i-osteoporosis kubantu abadala, ukungabikho komntwana, kunye nempilo yamazinyo nayo iyaqhubeka. Ngenxa yokuba i-CPP yi-peptide ekhutshwe kwiiprotheni zendalo kwaye ineenzuzo zokusabela okungalunganga, ukhuseleko kunye nokuthembeka, iya kusetyenziswa ngokubanzi. Ukusabela kwe-sensitization ye-casein, i-protein yobisi lwe-skim kunye ne-CPP ifundwe phesheya, kwaye ifunyenwe ukuba i-sensitization ye-CPP incinci kakhulu, ebonisa ukuba ingasetyenziselwa kumgaqo-siseko ochasene nobisi. Nangona kunjalo, kufuneka kuqatshelwe ukuba izinto ezichaphazela umphumo we-CPP zinzima kakhulu, kwaye indima yabo kwi-calcium metabolism isafuna ukuphuculwa.
Ixesha lokuposa: Jun-15-2023
