Ukulawula i-Addiction and Cravings nge-N-Acetylcysteine: Indlela esekelwe kubungqina

Ubukhoboka yimeko entsonkothileyo echaphazela izigidi zabantu ehlabathini lonke. Nokuba kukusebenzisa kakubi iziyobisi, ukungcakaza, okanye nayiphi na enye indlela yokuziphatha okunyanzelekileyo, ukuba likhoboka leziyobisi kunokuba neziphumo ezibi ebantwini nakubantu ababathandayo. Nangona kukho iindlela ezahlukeneyo zonyango ezikhoyo, i-N-Acetylcysteine ​​(NAC) iye yavela njengesixhobo esithembisayo ekulawuleni umlutha kunye neminqweno.

I-NAC yinto eyenzeka ngokwemvelo kwaye ifumaneka ngokubanzi njengesongezo sokutya ngendlela yomgubo. Ifundwe ngokubanzi malunga namandla ayo onyango, ngakumbi kwinkalo yobukhoboka. Uphando lubonise ukuba i-NAC inokunciphisa ngokufanelekileyo iminqweno kunye neempawu zokurhoxisa ezinxulumene nokulutha.

Enye yeendlela eziphambili apho i-NAC isebenza ngayo kukugcwalisa i-glutathione, i-antioxidant ebalulekileyo engqondweni. I-Glutathione inceda ukulawula inkqubo yomvuzo wengqondo, ephazamiseka kakhulu kumlutha. Ngokubuyisela amanqanaba e-glutathione, i-NAC inceda ukubuyisela kwakhona inkqubo yomvuzo, ukunciphisa iminqweno enzulu efunyanwa ngabantu abanomlutha.

Ngaphaya koko, i-NAC ifunyenwe imodareyitha iinkqubo ezininzi ze-neurotransmitter kwingqondo ezibandakanyekayo kumlutha. Ichaphazela amanqanaba e-dopamine, i-neurotransmitter ehambelana nolonwabo kunye nomvuzo, kunye ne-glutamate, i-neurotransmitter ebandakanyekayo ekufundeni nasekukhumbuleni. Ngokulawula ezi neurotransmitters, i-NAC inokunceda ukubuyisela ukusebenza kwengqondo eqhelekileyo kunye nokunciphisa umnqweno wokubandakanyeka ekuziphatheni okukhobokisayo.

Izifundo ezininzi zibonise ukusebenza kwe-NAC ekulawuleni umlutha kunye neminqweno. Uphononongo olupapashwe kwi-American Journal of Psychiatry lufumanise ukuba i-NAC yanciphisa kakhulu iminqweno ye-cocaine kunye nokuphucula izinga lokuziyeka kubantu abanomlutha we-cocaine. Olunye uphando olupapashwe kwiJenali ye-Clinical Psychopharmacology lubonise ukuba i-NAC yanciphisa iminqweno ye-nicotine kunye nokuphucula amazinga okuyeka ukutshaya kubantu abanomlutha wecuba.

I-NAC ikwabonise isithembiso ekuphatheni ezinye iziyobisi, ezifana nokungcakaza kunye nokulutha kwe-intanethi. Uphononongo olupapashwe kwijenali ye-Biological Psychiatry yaphonononga iziphumo ze-NAC kubantu abanengxaki yokungcakaza kwaye yafumanisa ukuba iyayinciphisa kakhulu iminqweno yokungcakaza kunye nezakhono eziphuculweyo zokuthatha izigqibo. Ngokufanayo, uphando olupapashwe kwiJenali ye-Clinical Psychopharmacology iphande iziphumo ze-NAC kumlutha we-intanethi kwaye yaxela ukuncitshiswa okubalulekileyo kweminqweno kunye nokuphucula ulawulo lwempembelelo.

Okubalulekileyo, ukusetyenziswa kwe-NAC ekulawuleni umlutha kuxhaswa bubungqina obuqinileyo besayensi. Kuye kwaphandwa ngokubanzi kuzo zombini izilwanyana kunye nezifundo zabantu, kunye neziphumo ezihambelanayo ezixhasa ukusebenza kwayo. Ukongeza, i-NAC ineprofayili yokhuseleko esekelwe kakuhle kwaye inyamezeleke ngokubanzi, iyenza ibe yinto efanelekileyo yokusetyenziswa kwexesha elide.

Ngelixa i-NAC ibonisa iziphumo ezithembisayo ekulawuleni umlutha kunye neminqweno, akufanele ijongwe njengonyango oluzimeleyo. Isebenza kakhulu xa isetyenziswa njengenxalenye yesicwangciso sonyango esibanzi esibandakanya unyango, iingcebiso, kunye namaqela enkxaso. I-NAC inokubonwa njengonyango oluncedisayo olunceda abantu ukuba bazibandakanye ngcono kwinkqubo yokubuyisela ngokunciphisa iminqweno kunye nokuphucula impilo yonke.

Ukuqukumbela, umlutha ngumba oxhaphakileyo ofuna iindlela zonyango ezisebenzayo. I-N-Acetylcysteine ​​(NAC) iye yavela njengesixhobo esithembisayo ekulawuleni umlutha kunye neminqweno. Ngokukwazi kwayo ukubuyisela ukusebenza kwengqondo, ukulungelelanisa iinkqubo ze-neurotransmitter, kunye nokunciphisa iminqweno, i-NAC inika ithemba kubantu abafuna ukuchacha. Nangona kunjalo, kubalulekile ukukhumbula ukuba i-NAC kufuneka isetyenziswe ngokubambisana nezinye iindlela zonyango kwiziphumo ezizezona zilungileyo. Ukuba wena okanye umntu omaziyo uyasokola, dibana nengcali yezempilo ukuze nixoxe ukuba i-NAC ilukhetho olufanelekileyo.